Integrative machine learning model of RNA modifications predict prognosis and treatment response in patients with breast cancer
Our study elucidates the significant role of RNA modifications in breast cancer prognosis and treatment. The CMRS model serves as a sensitive biomarker for predicting patient survival and treatment responsiveness, offering a new avenue for personalized therapy in patients with breast cancer.
Authors
- Jing Hou (ORCID: https://orcid.org/0000-0002-5845-6997)
- Shu Wang (ORCID: https://orcid.org/0000-0002-8651-4795)
- Qi Jia (ORCID: https://orcid.org/0000-0002-3168-3698)
- Jie Xie (ORCID: https://orcid.org/0000-0002-7618-5799)
- Zhuolin Li (ORCID: https://orcid.org/0009-0009-6991-3653)
- Tao Wang (ORCID: https://orcid.org/0009-0003-1825-0163)
Institutions
- Guizhou Provincial People's Hospital (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1186/s12935-025-03651-y
- Citations
- 8
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 6.45
Funders
- National Natural Science Foundation of China