Prehospital Whole Blood Administration Not Associated with Increased Transfusion Reactions: The Experience of a Metropolitan EMS Agency

Prehospital LTO+WB is safe to use and has a similar rate of transfusion reaction as when given in-hospital. Concerns about transfusion reactions caused by LTO+WB should not preclude its use prehospital. Regardless of the low incidence of transfusion reactions, prehospital personnel should be trained in their recognition and management. Limitations include retrospective study design and the inability to distinguish transfusion reactions from prehospital LTO+WB versus reaction to blood products transfused at the trauma center.

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Publication Details

Journal
Prehospital Emergency Care
Published
2025-02-13
DOI
https://doi.org/10.1080/10903127.2025.2464247
Citations
2
Primary Topic
Trauma, Hemostasis, Coagulopathy, Resuscitation
Type
article
Field-Weighted Citation Impact
3.09
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article

Prehospital Whole Blood Administration Not Associated with Increased Transfusion Reactions: The Experience of a Metropolitan EMS Agency

Emmanuel Giovanni Rayas, David Wampler, Donald H. Jenkins, William H. Bullock et al.
2 citations
Prehospital Emergency Care
Trauma, Hemostasis, Coagulopathy, Resuscitation
3.09
article

Prehospital Whole Blood Administration Not Associated with Increased Transfusion Reactions: The Experience of a Metropolitan EMS Agency

Emmanuel Giovanni Rayas, David Wampler, Donald H. Jenkins, William H. Bullock, Lauren Barry, Erika Brigmon, Jacquelyn Messenger, C Winckler, Vipulkumar Prajapati, Emily Raetz, Leslie Greebon, Rachel Ely, Brian G. Ferguson
article en
2 citations

Abstract

Prehospital LTO+WB is safe to use and has a similar rate of transfusion reaction as when given in-hospital. Concerns about transfusion reactions caused by LTO+WB should not preclude its use prehospital. Regardless of the low incidence of transfusion reactions, prehospital personnel should be trained in their recognition and management. Limitations include retrospective study design and the inability to distinguish transfusion reactions from prehospital LTO+WB versus reaction to blood products transfused at the trauma center.

Prehospital Emergency CareVol. 30(1)
Unifor (NO), Brooke Army Medical Center (US), New York City Fire Department (US), The University of Texas at San Antonio Health Science Center (US), Wilford Hall Ambulatory Surgical Center (US), San Antonio Uniformed Services Health Education Consortium (US), Joint Base San Antonio (US)
Good health and well-being
Openalex Percentile: Top 12%
Trauma, Hemostasis, Coagulopathy, Resuscitation
3.09
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Prehospital Whole Blood Administration Not Associated with Increased Transfusion Reactions: The Experience of a Metropolitan EMS Agency — Emmanuel Giovanni Rayas, David Wampler, et al. · Prehospital Emergency Care (2025) | TGRS Research Map | TGRS