HIF1α controls steroidogenesis under acute hypoxic stress

These findings elucidate the molecular mechanisms underlying acute hypoxia/HIF1α-induced changes in steroid biosynthesis and may also be useful in developing new strategies for various steroid hormone pathologies.

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Publication Details

Journal
Cell Communication and Signaling
Published
2025-02-13
DOI
https://doi.org/10.1186/s12964-025-02080-8
Citations
4
Primary Topic
Cancer, Hypoxia, and Metabolism
Type
article
Field-Weighted Citation Impact
3.75

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article

HIF1α controls steroidogenesis under acute hypoxic stress

Vasileia Ismini Alexaki, Ben Wielockx, Denise Kaden, Barbara K. Stepien et al.
4 citations
Cell Communication and Signaling
Cancer, Hypoxia, and Metabolism
3.75
article

HIF1α controls steroidogenesis under acute hypoxic stress

Vasileia Ismini Alexaki, Ben Wielockx, Denise Kaden, Barbara K. Stepien, Mangesh T. Jaykar, Mirko Peitzsch, Nicole Bechmann, Ali El‐Armouche, Deepika Watts, Peter Mirtschink, Stephen Ariyeloye, Cagdas Ermis, Anja Krüger
article en
4 citations

Abstract

These findings elucidate the molecular mechanisms underlying acute hypoxia/HIF1α-induced changes in steroid biosynthesis and may also be useful in developing new strategies for various steroid hormone pathologies.

Cell Communication and SignalingVol. 23(1)
Technische Universität Dresden (DE)
Deutsche Forschungsgemeinschaft, Technische Universität Dresden
Openalex Percentile: Top 8%
Cancer, Hypoxia, and Metabolism
3.75
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