Associations between fruit and vegetable consumption and HCC occurrence in patients with cirrhosis

The association between fruit and vegetable consumption and the risk of hepatocellular carcinoma (HCC) is poorly documented in the population of patients with cirrhosis, while such knowledge is crucial for adapting HCC prevention messages. Our study shows 57.5% of patients with cirrhosis reported consuming fruit and/or vegetables at or above the French and WHO threshold of 400 g/day, with a higher proportion of patients consuming at least 240 g/day of vegetables compared with those consuming at least 240 g/day of fruit (47.5% <i>vs.</i> 38.6%). The results suggest that consuming at least 240 g/day of vegetables reduces the risk of HCC by 65% in patients with cirrhosis.

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Publication Details

Journal
JHEP Reports
Published
2025-02-13
DOI
https://doi.org/10.1016/j.jhepr.2025.101355
Citations
2
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
2.71

Funders

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article

Associations between fruit and vegetable consumption and HCC occurrence in patients with cirrhosis

Alice Bellicha, Pierre Nahon, Chantal Julia, Léopold Fezeu et al.
2 citations
JHEP Reports
Liver Disease Diagnosis and Treatment
2.71
article

Associations between fruit and vegetable consumption and HCC occurrence in patients with cirrhosis

Alice Bellicha, Pierre Nahon, Chantal Julia, Léopold Fezeu, Nathalie Ganne‐Carrié, Florian Manneville, Mathilde Touvier, Zineb Zouakia, Séverine Donneger
article en
2 citations

Abstract

The association between fruit and vegetable consumption and the risk of hepatocellular carcinoma (HCC) is poorly documented in the population of patients with cirrhosis, while such knowledge is crucial for adapting HCC prevention messages. Our study shows 57.5% of patients with cirrhosis reported consuming fruit and/or vegetables at or above the French and WHO threshold of 400 g/day, with a higher proportion of patients consuming at least 240 g/day of vegetables compared with those consuming at least 240 g/day of fruit (47.5% <i>vs.</i> 38.6%). The results suggest that consuming at least 240 g/day of vegetables reduces the risk of HCC by 65% in patients with cirrhosis.

JHEP ReportsVol. 7(5)
Conservatoire National des Arts et Métiers (FR), Inserm (FR), Université Paris Cité (FR), Sorbonne Université (FR), Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR), Université Sorbonne Paris Nord (FR), Centre de Recherche des Cordeliers (FR), Assistance Publique – Hôpitaux de Paris (FR), Hôpital Avicenne (FR), Centre de Recherche Épidémiologie et Statistique (FR)
HORIZON EUROPE Framework Programme
Zero hunger
Openalex Percentile: Top 12%
Liver Disease Diagnosis and Treatment
2.71
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Associations between fruit and vegetable consumption and HCC occurrence in patients with cirrhosis — Alice Bellicha, Pierre Nahon, et al. · JHEP Reports (2025) | TGRS Research Map | TGRS