Depression and physical multimorbidity: A cohort study of physical health condition accrual in UK Biobank
Middle-aged and older adults with a history of depression have more long-term physical health conditions at baseline and accrue additional physical conditions at a faster rate than those without a history of depression. Our findings highlight the importance of integrated approaches to managing both mental and physical health outcomes.
Authors
- Regina Prigge (ORCID: https://orcid.org/0000-0002-0489-684X)
- Daniel R. Morales (ORCID: https://orcid.org/0000-0002-0063-8069)
- Caroline Jackson (ORCID: https://orcid.org/0000-0002-2067-2811)
- Daniel J. Smıth (ORCID: https://orcid.org/0000-0002-2267-1951)
- Paul A. Kelly (ORCID: https://orcid.org/0000-0001-6997-9788)
- Stewart W Mercer (ORCID: https://orcid.org/0000-0002-1703-3664)
- John Norrie (ORCID: https://orcid.org/0000-0001-9823-9252)
- Bruce Guthrie (ORCID: https://orcid.org/0000-0003-4191-4880)
- Kelly Fleetwood (ORCID: https://orcid.org/0000-0002-1382-3095)
- Cathie Sudlow (ORCID: https://orcid.org/0000-0002-7725-7520)
Institutions
- University of Dundee (GB)
- Health Data Research UK (GB)
- Genomics (United Kingdom) (GB)
- University of Edinburgh (GB)
Publication Details
- Journal
- PLoS Medicine
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1371/journal.pmed.1004532
- Citations
- 22
- Primary Topic
- Chronic Disease Management Strategies
- Type
- article
- Field-Weighted Citation Impact
- 29.79
Funders
- Medical Research Council