Insulin‐Like Growth Factor 2 <scp>mRNA</scp> ‐Binding Protein 2 ( <scp>IGF2BP2</scp> ) Promotes Castration‐Resistant Prostate Cancer Progression by Regulating <scp>AR</scp> ‐ <scp>V7 mRNA</scp> Stability
Taken together, our findings suggest that IGF2BP2 plays a critical role in regulating AR-V7 expression and stability, offering a novel target for developing therapeutic interventions for CRPC.
Authors
- Ashish Misra (ORCID: https://orcid.org/0000-0002-3042-8302)
- Devesh Srivastava (ORCID: https://orcid.org/0000-0002-6644-3619)
- Parul Mishra (ORCID: https://orcid.org/0000-0002-2989-7371)
- Rajnikant Raut (ORCID: https://orcid.org/0000-0001-6963-5889)
- Taruna Saini
Institutions
- University of Hyderabad (IN)
- Indian Institute of Technology Hyderabad (IN)
Publication Details
- Journal
- Cancer Reports
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/cnr2.70096
- Citations
- 4
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- Johns Hopkins University
- Department of Biotechnology, Ministry of Science and Technology, India
- Indian Council of Medical Research
- Ministry of Education, India