MedKAFormer: When Kolmogorov–Arnold Theorem Meets Vision Transformer for Medical Image Representation
Vision Transformers (ViTs) suffer from high parameter complexity because they rely on Multi-layer Perceptrons (MLPs) for nonlinear representation. This issue is particularly challenging in medical image analysis, where labeled data is limited, leading to inadequate feature representation. Existing methods have attempted to optimize either the patch embedding stage or the non-embedding stage of ViTs. Still, they have struggled to balance effective modeling, parameter complexity, and data availability. Recently, the Kolmogorov-Arnold Network (KAN) was introduced as an alternative to MLPs, offering a potential solution to the large parameter issue in ViTs. However, KAN cannot be directly integrated into ViT due to challenges such as handling 2D structured data and dimensionality catastrophe. To solve this problem, we propose MedKAFormer, the first ViT model to incorporate the Kolmogorov-Arnold (KA) theorem for medical image representation. It includes a Dynamic Kolmogorov-Arnold Convolution (DKAC) layer for flexible nonlinear modeling in the patch embedding stage. Additionally, it introduces a Nonlinear Sparse Token Mixer (NSTM) and a Nonlinear Dynamic Filter (NDF) in the non-embedding stage. These components provide comprehensive nonlinear representation while reducing model overfitting. MedKAFormer reduces parameter complexity by 85.61% compared to ViT-Base and achieves competitive results on 14 medical datasets across various imaging modalities and structures.
Authors
- Benzheng Wei (ORCID: https://orcid.org/0000-0001-9640-4947)
- Qikui Zhu (ORCID: https://orcid.org/0000-0002-2779-4766)
- Shuo Li (ORCID: https://orcid.org/0000-0002-5184-3230)
- Guoli Wang (ORCID: https://orcid.org/0009-0009-5038-5184)
- Chaoda Song (ORCID: https://orcid.org/0009-0001-5392-6304)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Case Western Reserve University (US)
Publication Details
- Journal
- IEEE Journal of Biomedical and Health Informatics
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1109/jbhi.2025.3541982
- Citations
- 8
- Primary Topic
- Medical Image Segmentation Techniques
- Type
- article
- Field-Weighted Citation Impact
- 10.21
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province