Differences in tumor angiogenesis and related factors between lung adenocarcinomas manifesting as pure ground glass opacity and solid nodules
Our finding displays that GGO-LUAD was significantly lower than SN-LUAD in CD34 + MVD and CD105 + MVD reflecting tumor angiogenesis, and the distribution of CAFs and factors related to tumor angiogenesis were also significantly lower in GGO-LUAD, which may indicate that the weak ability of angiogenesis might be the reason for the good prognosis of GGO-LUAD.
Authors
- Shenghui Qin (ORCID: https://orcid.org/0000-0002-0275-133X)
- Rirong Qu (ORCID: https://orcid.org/0000-0002-3334-3304)
- Dehao Tu (ORCID: https://orcid.org/0000-0002-4652-9466)
- Jing Xiong (ORCID: https://orcid.org/0000-0003-2771-7565)
- Xiangning Fu (ORCID: https://orcid.org/0000-0003-4670-1438)
- Yang Zhang (ORCID: https://orcid.org/0000-0002-1317-120X)
- Lequn Li (ORCID: https://orcid.org/0000-0002-6582-142X)
- Yixin Cai
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Yueyang Second People's Hospital (CN)
- Yueyang Hospital (CN)
- Wuhan Children's Hospital (CN)
- Tongji Hospital (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1007/s12672-025-01898-5
- Citations
- 1
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.32
Funders
- China Postdoctoral Science Foundation
- Tongji University