<scp>circNR3C2</scp> promotes chondrogenic differentiation and cartilage repair of human adipose‐derived stem cells via the hsa‐ <scp>miR</scp> ‐647/ <scp>SOX9</scp> pathway
We show that circNR3C2 modulates SOX9 expression to promote hsa-miR-647-mediated hADSC chondrogenic differentiation; targeting circNR3C2 may help to develop new treatments to manage cartilage-related disorders.
Authors
- Dabiao Hou (ORCID: https://orcid.org/0009-0001-4651-6470)
- Duan Luo (ORCID: https://orcid.org/0000-0001-5926-9870)
- Simin Luo (ORCID: https://orcid.org/0000-0001-9001-6935)
- Xiaofei Zheng (ORCID: https://orcid.org/0000-0001-7502-6131)
- Hao Guo (ORCID: https://orcid.org/0000-0002-3557-8289)
- Huajun Wang (ORCID: https://orcid.org/0000-0003-3936-7400)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Jinan University (CN)
- First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
- First Affiliated Hospital of Jinan University (CN)
Publication Details
- Journal
- Animal Models and Experimental Medicine
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1002/ame2.12561
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Jinan University
- Fundamental Research Funds for the Central Universities