Detection of Overlooked Rare <scp><i>EGFR</i></scp> Mutations in Non‐small Cell Lung Cancer Using Multigene Testing

ODxTT failed to identify 10 actionable EGFR mutations, accounting for 12.2% (10/82) of the cases initially reported as not carrying actionable mutations. Therefore, comprehensive genomic profiling should be actively performed early in cases with high clinical suspicion of EGFR mutations.

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Publication Details

Journal
Thoracic Cancer
Published
2025-02-01
DOI
https://doi.org/10.1111/1759-7714.70007
Citations
2
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
3.04

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article

Detection of Overlooked Rare EGFR Mutations in Non‐small Cell Lung Cancer Using Multigene Testing

Kazuto Nishio, Kazuko Sakai, Chiaki Inagaki, Hidetoshi Hayashi et al.
2 citations
Thoracic Cancer
Lung Cancer Treatments and Mutations
3.04
article

Detection of Overlooked Rare EGFR Mutations in Non‐small Cell Lung Cancer Using Multigene Testing

Kazuto Nishio, Kazuko Sakai, Chiaki Inagaki, Hidetoshi Hayashi, Kimio Yonesaka, Hiroaki Kanemura, Tsutomu Iwasa, Yusuke Kawanaka, Kazuhiko Nakagawa, Takayuki Takahama, Junko Tanizaki, Tetsuya Mitsudomi, Shinichiro Suzuki, Kaoru Tanaka, Tomohiro Nakayama, Takashi Kurosaki, Kazuya Fukuoka, Yuzuki Nakagawa, N. Shiraishi
article en
2 citations

Abstract

ODxTT failed to identify 10 actionable EGFR mutations, accounting for 12.2% (10/82) of the cases initially reported as not carrying actionable mutations. Therefore, comprehensive genomic profiling should be actively performed early in cases with high clinical suspicion of EGFR mutations.

Thoracic CancerVol. 16(3)
Kindai University Hospital (JP), Kishiwada City Hospital (JP), Izumi City General Hospital (JP), Kindai University (JP)
Amgen, Bristol-Myers Squibb, Eli Lilly and Company, Pfizer, AstraZeneca, Boehringer Ingelheim Japan, Kanazawa University, Otsuka Pharmaceutical, Yakult Honsha, SymBio Pharmaceuticals Limited, Novartis Pharma, Pfizer Japan, Chugai Pharmaceutical, Eli Lilly Japan, Daiichi Sankyo Europe
Good health and well-being
Openalex Percentile: Top 11%
Lung Cancer Treatments and Mutations
3.04
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