Prevalence and Associated Factors of Breast Cancer Women’s Quality of Life

Background: Breast cancer is the leading cause of cancer deaths in women. (BC) is the second-most prevalent type of cancer overall and the most common malignancy in women. Around 2.1 million people received breast cancer diagnosis globally in 2018, and the disease claimed the lives of about 627,000 people. In the contemporary healthcare system, quality of life has become a key concern for evaluating people's subjective perceptions of their lives. There have also been reports of psychological effects such as anxiety, melancholy, dread, and a decline in life satisfaction. These outcomes adversely affect both health and quality of life (QoL). Objective: to determine the Prevalence of breast cancer and the associated risk factors with QoL among women diagnosed with breast cancer (BC). Methods: A cross-sectional study included 200 women patients with breast cancer admitted to Al-Azhar University Hospitals from April 2023 to October 2024. the quality-of-life index-cancer ranged from 17.54-24.12 with a mean of 21, 70±3.89. Results: Out of the 200 patients who were allocated in the current retrospective study, 35 women with stage 1, 60 women with stage 2, and 50 women with stage 3 as well as 55 women with stage 4. While monthly income had a highly significant positive correlation with the quality of life in soccer (r=0.613, p=0.021) and (HADS depression, HADS anxiety, MFIS, PSQI total score, FSFI, IPAQ) there was a significant negative correlation between them. Cox-regression analysis indicated that the most important independent risk factors associated with breast cancer women’s quality of life were cancer stage. However, the duration of disease and cancer stage had a highly significant negative correlation with the quality-of-life score (r= -0.455, p=0.036) and (r= -0.392, p=0.39), respectively. Cox-regression analysis indicated that the most significant independent risk factors associated with breast cancer women’s quality of life were cancer stage (OR:2.45, 95%CI, 0.098-0.298, p=0.013), HADS depression (OR:2.812, 95%CI, 0.987-3.761, p=0.007), PSQI total score (OR:5.16, 95%CI, 2.54-9.21, p=0.006), and IPAQ (OR:1.09, 95%CI, 0.158-1.499, p=0.013). Conclusions: QoL assessments could help professionals prioritize problems, communicate more effectively with patients, minimize adversity, and determine patient preferences. We discovered a bad quality of life among people with breast cancer under study. The stage of cancer, anxiety and despair scale, modified fatigue effect scale, and female sexual function index all had a substantial impact on breast cancer women's quality of life.