Binding studies of Ru(II) complex with DNA isolated from chicken liver extract

Ruthenium polypyridyl complexes have garnered attention due to their promising coordination chemistry and potential applications in biological and photophysical research. This study investigates the synthesis and binding properties of [Ru(NN)3]2+ complexes (where NN= bpy,dmbpy) with DNA models like chicken liver DNA. Using UV – Visible and emission spectroscopy, significant bathochromic shifts were observed, indicating strong interactions and possible intercalative binding. The results highlight the unique affinity and photophysical behavior of Ruthenium polypyridyl complexes, contributing to a deeper understanding of their potential probes as therapeutic agents. The research opens avenues forfuture explorations in medical and agricultural chemistry.