The role of rhBMP-2 in mandibular bone regeneration following tooth extraction through HIF-1α and VEGF-A expression: An Immunohistochemical study
Our study suggests that injecting rhBMP-2 into the grafted material and socket extraction during GBR dramatically increases the expression of VEGF-A and HIF-1α. These findings have the potential to significantly impact oral surgery and regenerative dentistry, opening up new possibilities for enhancing bone regeneration techniques.
Authors
- Ira Kusuma Dewi (ORCID: https://orcid.org/0009-0002-9851-7114)
- Christian Khoswanto (ORCID: https://orcid.org/0000-0001-5589-1259)
Institutions
- University of Surabaya (ID)
- Universitas Airlangga (ID)
Publication Details
- Journal
- Journal of Oral Biology and Craniofacial Research
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1016/j.jobcr.2025.02.001
- Citations
- 2
- Primary Topic
- Periodontal Regeneration and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.67