Exploring the Trade-Offs: Unified Large Language Models vs Local Fine-Tuned Models for Highly-Specific Radiology NLI Task
Recently, ChatGPT and GPT-4 have emerged and gained immense global attention due to their unparalleled performance in language processing. Despite demonstrating impressive capability in various open-domain tasks, their adequacy in highly specific fields like radiology remains untested. Radiology presents unique linguistic phenomena distinct from open-domain data due to its specificity and complexity. Assessing the performance of large language models (LLMs) in such specific domains is crucial not only for a thorough evaluation of their overall performance but also for providing valuable insights into future model design directions: whether model design should be generic or domain-specific. To this end, in this study, we evaluate the performance of ChatGPT/GPT-4 on a radiology natural language inference (NLI) task and compare it to other models fine-tuned specifically on task-related data samples. We also conduct a comprehensive investigation on ChatGPT/GPT-4’s reasoning ability by introducing varying levels of inference difficulty. Our results show that 1) ChatGPT and GPT-4 outperform other LLMs in the radiology NLI task and 2) other specifically fine-tuned Bert-based models require significant amounts of data samples to achieve comparable performance to ChatGPT/GPT-4. These findings not only demonstrate the feasibility and promise of constructing a generic model capable of addressing various tasks across different domains, but also highlight several key factors crucial for developing a unified model, particularly in a medical context, paving the way for future artificial general intelligence (AGI) systems. We release our code and data to the research community.
Authors
- Dinggang G. Shen (ORCID: https://orcid.org/0000-0002-7934-5698)
- Lu Zhang (ORCID: https://orcid.org/0000-0002-8859-5453)
- Zihao Wu (ORCID: https://orcid.org/0000-0002-4389-2980)
- Dajiang Zhu (ORCID: https://orcid.org/0000-0002-6940-3911)
- Haixing Dai (ORCID: https://orcid.org/0000-0003-0409-6129)
- Quanzheng Li (ORCID: https://orcid.org/0000-0002-9651-5820)
- Xiaowei Yu (ORCID: https://orcid.org/0000-0002-5599-8424)
- Xiang Li (ORCID: https://orcid.org/0000-0002-3423-5065)
- Lin Zhao (ORCID: https://orcid.org/0000-0003-2567-627X)
- Chong Ma (ORCID: https://orcid.org/0009-0001-8192-9676)
- Wei Liu (ORCID: https://orcid.org/0000-0001-9475-6455)
- Gang Li (ORCID: https://orcid.org/0000-0001-9585-1382)
- Yiwei Li (ORCID: https://orcid.org/0000-0002-5203-0290)
- Tianming Liu
- Chao Cao (ORCID: https://orcid.org/0009-0009-6844-519X)
- Zhengliang Liu (ORCID: https://orcid.org/0000-0001-7061-6714)
Institutions
- University of North Carolina at Chapel Hill (US)
- Harvard University (US)
- University of Georgia (US)
- Northwestern Polytechnical University (CN)
- The University of Texas at Arlington (US)
- WinnMed (US)
- ShanghaiTech University (CN)
- Massachusetts General Hospital (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- IEEE Transactions on Big Data
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1109/tbdata.2025.3536928
- Citations
- 8
- Primary Topic
- Topic Modeling
- Type
- article
- Field-Weighted Citation Impact
- 17.37