The Bad Reputation of Digoxin in Atrial Fibrillation—Causality or Bias? Nationwide Nested Case-Control Study
Digoxin use was associated with increased mortality in AF. However, negative control outcomes were also associated with digoxin use indicating that the described association between digoxin and mortality is likely not causal and being prescribed digoxin is merely a marker of more advanced disease and frailty.
Authors
- Morten Lock Hansen (ORCID: https://orcid.org/0000-0001-7996-5005)
- Peter Rasmussen (ORCID: https://orcid.org/0000-0002-4593-3854)
- Morten Lamberts (ORCID: https://orcid.org/0000-0002-9827-440X)
- Jarl Emanuel Strange (ORCID: https://orcid.org/0000-0002-1803-5266)
- Anders Holt (ORCID: https://orcid.org/0000-0002-8196-2599)
Institutions
- University of Copenhagen (DK)
- Gentofte Hospital (DK)
Publication Details
- Journal
- American Journal of Medicine Open
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1016/j.ajmo.2025.100093
- Citations
- 2
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.78