Diffuse changes in the brain in the acute phase of COVID-19 and after infection

The identified neuropathological changes in COVID-19 in the acute and post-infectious phases are nonspecific with a predominance of vascular disorders and microglial reaction and are most pronounced in the brain stem and cerebellum. The SARS-CoV-2 S1 protein can accumulate in neurons and be detected in the brain a year or more after infection.

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Publication Details

Journal
Russian Journal of Archive of Pathology
Published
2025-02-12
DOI
https://doi.org/10.17116/patol2025870115
Primary Topic
Long-Term Effects of COVID-19
Type
article
Field-Weighted Citation Impact
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article

Diffuse changes in the brain in the acute phase of COVID-19 and after infection

П Л Ануфриев, A. А. Kanibolotskiy, Anna N. Berliand
Russian Journal of Archive of Pathology
Long-Term Effects of COVID-19
article

Diffuse changes in the brain in the acute phase of COVID-19 and after infection

П Л Ануфриев, A. А. Kanibolotskiy, Anna N. Berliand
article en

Abstract

The identified neuropathological changes in COVID-19 in the acute and post-infectious phases are nonspecific with a predominance of vascular disorders and microglial reaction and are most pronounced in the brain stem and cerebellum. The SARS-CoV-2 S1 protein can accumulate in neurons and be detected in the brain a year or more after infection.

Russian Journal of Archive of PathologyVol. 87(1)
Research Institute of Emergency Care (RU), Research Center of Neurology (RU)
Good health and well-being
Openalex Percentile: Top 95%
Long-Term Effects of COVID-19
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