1-methylnicotinamide modulates IL-10 secretion and voriconazole metabolism
1-MNA regulated Kupffer cell polarization in an LPS-induced inflammatory environment, reduced the inflammatory inhibition of CYP2C38 expression in hepatocytes, and promoted VRC metabolism.
Authors
- Yuanqing Li (ORCID: https://orcid.org/0000-0003-2083-4339)
- Lin Jiang (ORCID: https://orcid.org/0000-0002-7114-0794)
- Xiaoyan Deng (ORCID: https://orcid.org/0000-0003-0186-8234)
- Xiaokang Wang (ORCID: https://orcid.org/0000-0002-4325-9907)
- Xuqiu Xie
Institutions
- Longgang Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-02-13
- DOI
- https://doi.org/10.3389/fimmu.2025.1529660
- Citations
- 8
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 11.17
Funders
- Southern Medical University
- Shenzhen Hospital, Southern Medical University