[Analysis of relevant factors for rupture of basilar tip aneurysms].

<b>Objective:</b> To investigate the relevant factors for rupture of basilar tip aneurysms. <b>Methods:</b> This is a retrospective cohort study. Patients who underwent cerebrovascular digital subtraction angiography at Department of Cerebrovascular Disease Surgery,Zhujiang Hospital of Southern Medical University from July 2008 to February 2023 and were confirmed to have basilar tip aneurysms were retrospectively analyzed. There were 45 males and 56 females, aged (57.5±10.2) years (range: 36 to 76 years); the maximum diameter of the basilar tip aneurysm (<i>M</i>(IQR)) was 6.85 (5.79) mm (range: 1.28 to 27.48 mm). Finally, 101 basilar tip aneurysms were included, and divided into two groups based on whether the basilar tip aneurysm ruptured or not. There were 37 cases (36.6%) in the ruptured group and 64 cases (63.4%) in the unruptured group. Data were analyzed using independent <i>t</i>-test, Mann-Whitney <i>U</i> test, chi-square test, or Fisher's exact test, as appropriate, and predictive factors for rupture of basilar tip aneurysms were explored by Logistic regression analysis. Variance inflation factors was used for analysis of collinearity. <b>Results:</b> The univariate results showed statistically significant differences between the ruptured and unruptured groups in terms of aneurysm neck width, basilar artery diameter, mean diameter of the parental artery, the ratio of neck width to parent artery diameter, aneurysm width and maximum diameter of the aneurysm (all <i>P</i><0.05). In multivariate analysis, basilar artery diameter (<i>OR</i>=0.347, 95%<i>CI</i>:0.176 to 0.687, <i>P</i>=0.002), and NRP (<i>OR</i>=0.366, 95%<i>CI</i>:0.192 to 0.696, <i>P</i>=0.002) were predictive factors for rupture of aneurysms occurring at the basilar tip. There was no multiple covariance between NRP and basilar artery diameter in the analysis of covariance (VIF=1). <b>Conclusion:</b> Smaller basilar artery diameter and smaller NRP are relevant factors for rupture of basilar tip aneurysms.