Physical activity, genetic susceptibility, and risk of colorectal cancer in type 2 diabetes: a large population-based cohort study
Our study suggests that moderate to high PA helps to reduce the risk of CRC in T2D patients and that joint consideration of PA level and PRS could provide valuable insights for personalized strategies to prevent CRC.
Authors
- Felix W. Leung (ORCID: https://orcid.org/0000-0002-8313-8464)
- Weihong Sha (ORCID: https://orcid.org/0000-0001-7610-3813)
- Meijun Meng
- Chongyang Duan (ORCID: https://orcid.org/0000-0001-7973-0353)
- Qizhou Lian (ORCID: https://orcid.org/0000-0001-8189-7160)
- Yuying Ma
- Hao Chen (ORCID: https://orcid.org/0000-0003-0857-7405)
- Yufeng Liu (ORCID: https://orcid.org/0000-0002-9472-9104)
- Wentao Huang (ORCID: https://orcid.org/0000-0002-7872-8996)
- Yanjun Wu (ORCID: https://orcid.org/0000-0002-4379-8230)
- Ruijie Zeng (ORCID: https://orcid.org/0000-0002-9803-0157)
- Jing Feng (ORCID: https://orcid.org/0000-0003-0604-3581)
- Lijun Zhang (ORCID: https://orcid.org/0000-0003-4974-2745)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Guangdong Academy of Medical Sciences (CN)
Publication Details
- Journal
- Deutsches Ärzteblatt international
- Published
- 2025-03-27
- DOI
- https://doi.org/10.3238/arztebl.m2025.0013
- Primary Topic
- Metabolism, Diabetes, and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00