Plasma Hepcidin as a potential informative biomarker of Alzheimer disease and vascular dementia
Blood Hepcidin and NfL have limited interest in the clinical context of AD but determination of these biomarkers shows to be highly informative for the diagnosis of VaD. This result could have important implications for diagnosis and implementation of clinical trials.
Authors
- Xavier Ayrignac (ORCID: https://orcid.org/0000-0003-3834-2981)
- Juan Fortea (ORCID: https://orcid.org/0000-0002-1340-638X)
- Alberto Lleó (ORCID: https://orcid.org/0000-0002-2568-5478)
- Audrey Gabelle (ORCID: https://orcid.org/0000-0002-7648-9194)
- Sylvain Lehmann (ORCID: https://orcid.org/0000-0001-6117-562X)
- Shaima El Bounasri
- Christophe Hirtz (ORCID: https://orcid.org/0000-0002-7313-0629)
- Germain U. Busto (ORCID: https://orcid.org/0000-0002-8787-563X)
- Constance Delaby (ORCID: https://orcid.org/0000-0002-8606-6814)
- Karim Bennys (ORCID: https://orcid.org/0000-0003-1363-0143)
- Elena Muiño (ORCID: https://orcid.org/0000-0001-5839-7328)
- Henrik Zetterberg (ORCID: https://orcid.org/0000-0003-3930-4354)
- Israel Fernández‐Cadenas (ORCID: https://orcid.org/0000-0003-4821-2363)
- Daniel Andres Alcolea (ORCID: https://orcid.org/0000-0002-3819-3245)
- Nicolas Pradeilles
- Soraya Torres
- Paula Villatoro
Institutions
- University of Wisconsin–Madison (US)
- Inserm (FR)
- Université de Montpellier (FR)
- Sahlgrenska University Hospital (SE)
- Hospital de Sant Pau (ES)
- Biomedical Research Networking Center on Neurodegenerative Diseases (ES)
- UK Dementia Research Institute (GB)
- National Hospital for Neurology and Neurosurgery (GB)
- University College London (GB)
- University of Gothenburg (SE)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1186/s13195-025-01696-9
- Citations
- 8
- Primary Topic
- Iron Metabolism and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 14.16
Funders
- Alzheimer's Association
- Alzheimer's Drug Discovery Foundation
- Familjen Erling-Perssons Stiftelse
- Cure Alzheimer's Fund
- Stiftelsen för Gamla Tjänarinnor
- EU Joint Programme – Neurodegenerative Disease Research
- National Institute for Health and Care Research
- University College London
- European Commission
- Fondation Jérôme Lejeune
- Generalitat de Catalunya
- Hjärnfonden
- Vetenskapsrådet
- Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas
- UK Dementia Research Institute
- National Institutes of Health
- HORIZON EUROPE Framework Programme
- Instituto de Salud Carlos III
- European Regional Development Fund
- National Institute on Aging