Itaconate facilitates methane-induced Nrf2 pathway activation for mitigating liver ischemia and reperfusion injury
Methane alleviates liver IRI through itaconate/Nrf2 pathway activation, with itaconate being critical for methane's beneficial effects.
Authors
- Tianyi Zhang (ORCID: https://orcid.org/0000-0003-4028-1663)
- Hongtao Lu (ORCID: https://orcid.org/0000-0002-0414-5798)
- Linwei Zhao
- Zhouheng Ye (ORCID: https://orcid.org/0000-0001-8070-7943)
- Qiang Sun (ORCID: https://orcid.org/0000-0002-9572-4970)
- Kexin Liu (ORCID: https://orcid.org/0000-0002-0699-8452)
- Dan-Feng Fan
- Kewei Qin
- Pei Zhang (ORCID: https://orcid.org/0009-0006-5239-8286)
Institutions
- Naval University of Engineering (CN)
- Chinese PLA General Hospital (CN)
- South China University of Technology (CN)
Publication Details
- Journal
- iLiver
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1016/j.iliver.2025.100144
- Citations
- 1
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 1.32
Funders
- Innovative Research Group Project of the National Natural Science Foundation of China
- National Natural Science Foundation of China
- Natural Science Foundation of Beijing Municipality
- Beijing Municipal Natural Science Foundation