Discovery of plasma proteins and metabolites associated with left ventricular cardiac dysfunction in pan-cancer patients
Our findings suggest that circulating metabolites may non-invasively detect clinical and molecular differences in patients with LVD, providing insights into underlying disease pathways and potential therapeutic targets.
Authors
- Feixiong Cheng (ORCID: https://orcid.org/0000-0002-1736-2847)
- Michelle Fang (ORCID: https://orcid.org/0000-0003-1548-010X)
- Reina Tonegawa‐Kuji (ORCID: https://orcid.org/0000-0001-7998-939X)
- Jessica C. Lal (ORCID: https://orcid.org/0000-0001-5462-2671)
- Patrick Collier (ORCID: https://orcid.org/0000-0003-3941-9653)
- Mina K. Chung (ORCID: https://orcid.org/0000-0002-7835-6045)
- Muzna Hussain (ORCID: https://orcid.org/0000-0003-1533-6634)
- Yuan Hou
- Abel Abraham
Institutions
- Cleveland Clinic (US)
- The University of Texas MD Anderson Cancer Center (US)
- Cleveland Clinic Lerner College of Medicine (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- Cardio-Oncology
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1186/s40959-025-00309-6
- Citations
- 1
- Primary Topic
- Chemotherapy-induced cardiotoxicity and mitigation
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Cancer Prevention and Research Institute of Texas
- Cleveland Clinic
- National Heart, Lung, and Blood Institute