Federal clinical guidelines on diagnosis and treatment of hypersensitivity pneumonitis
Hypersensitivity pneumonitis (HP) is an inflammatory and/or fibrotic lung disease that occurs in response to repeated inhalation of broad-spectrum aerosol antigens. The prevalence of HP ranges from 0.3 to 0.9 cases per 100,000 population. The basis treatment of HP therapy includes glucocorticoids, immunosuppressants, and antifibrotic drugs. The target audience of these clinical recommendations are general practitioners, pulmonologists, pathologists, radiologists, and medical rehabilitation specialists. Methods. Each thesis-recommendation for diagnostic and therapeutic measures is evaluated on a scale of evidence reliability from 1 to 5 and a scale of the recommendation persuasiveness with the categories A, B, C. The guidelines also contain comments and explanations to these thesis-recommendations, algorithms for the diagnosis and treatment of idiopathic pulmonary fibrosis, and reference materials. Conclusion. The presented clinical guidelines cover current information about the etiology and pathogenesis, clinical manifestations, diagnosis, and treatment of hypersensitivity pneumonitis. These guidelines were approved by the Scientific and Practical Council of the Ministry of Health of the Russian Federation in 2023.
Authors
- И. В. Демко (ORCID: https://orcid.org/0000-0001-8982-5292)
- Sergey Nikolaevich Avdeev (ORCID: https://orcid.org/0000-0002-5999-2150)
- S. Yu. Chikina (ORCID: https://orcid.org/0000-0002-5536-9388)
- А. A. Vizel (ORCID: https://orcid.org/0000-0001-5028-5276)
- V. D. Fedotov (ORCID: https://orcid.org/0000-0003-4307-9321)
- З. Р. Айсанов (ORCID: https://orcid.org/0000-0002-4044-674X)
- I. Е. Tyurin (ORCID: https://orcid.org/0000-0003-3931-1431)
- A. L. Chernyaev (ORCID: https://orcid.org/0000-0002-0158-7056)
- И. Н. Трофименко (ORCID: https://orcid.org/0000-0003-2742-3794)
- M. F. Kinyaikin (ORCID: https://orcid.org/0000-0002-5498-9008)
- М. В. Самсонова (ORCID: https://orcid.org/0000-0001-8170-1260)
- B. A. Chernyak (ORCID: https://orcid.org/0000-0002-5902-6198)
- О. Н. Титова (ORCID: https://orcid.org/0000-0003-4678-3904)
- Orlova Gp (ORCID: https://orcid.org/0000-0002-3374-9320)
- Е. И. Шмелев (ORCID: https://orcid.org/0000-0002-1908-5601)
- M. M. Ilkovich (ORCID: https://orcid.org/0000-0001-5191-445X)
- И. В. Лещенко (ORCID: https://orcid.org/0000-0002-1620-7159)
- Н. В. Трушенко (ORCID: https://orcid.org/0000-0002-0685-4133)
Institutions
- Privolzhsky Research Medical University (RU)
- Sechenov University (RU)
- Kazan State Medical University (RU)
- First Pavlov State Medical University of St. Petersburg (RU)
- Pirogov Russian National Research Medical University (RU)
- Krasnoyarsk State Medical University (RU)
- Ural State Medical University (RU)
- Tver State Medical University (RU)
- Russian Medical Academy of Continuous Professional Education (RU)
- Ministry of Health of the Russian Federation (RU)
- Krasnoyarsk Regional Clinical Hospital (RU)
- Central Scientific Research Institute of Tuberculosis Russian Academy of Medical Sciences (RU)
- Research Institute of Human Morphology (RU)
- Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (RU)
- Ural research Institute of Phthisiopulmonology (RU)
- Irkutsk State Medical University (RU)
Publication Details
- Journal
- PULMONOLOGIYA
- Published
- 2025-02-12
- DOI
- https://doi.org/10.18093/0869-0189-2025-35-1-16-41
- Citations
- 4
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 6.07
Funders
- Ministry of Science and Higher Education of the Russian Federation