MK2 Inhibition in CD4+ T Cells Protects Against IFNγ and IL-17A, Chronic Inflammation, and Fibrosis in Inflammatory Bowel Disease Models
The MK2 pathway regulates inflammatory CD4+ T cells and fibrosis in IBD models and is a potential therapeutic target.
Authors
- Cody Howe (ORCID: https://orcid.org/0000-0003-3665-3567)
- Ellen J. Beswick (ORCID: https://orcid.org/0000-0003-3538-3040)
- Marina Chulkina (ORCID: https://orcid.org/0000-0003-2840-937X)
- Steven McAninch
- Christina McAninch
- Ryan Syrcle
- Irina V. Pinchuk
Institutions
- University of Kentucky (US)
- Penn State Milton S. Hershey Medical Center (US)
Publication Details
- Journal
- Inflammatory Bowel Diseases
- Published
- 2025-01-26
- DOI
- https://doi.org/10.1093/ibd/izaf026
- Citations
- 3
- Primary Topic
- Melanoma and MAPK Pathways
- Type
- article
- Field-Weighted Citation Impact
- 2.42