Expression of Cyclin D1 and Claudin-1 in Invasive Breast Carcinoma and Their Correlation with Clinicopathological Parameters

Our findings advocated the expression of IHC namely, cyclin D1 and claudin-1, in cases of breast cancer. Cyclin D1 positivity may show a significant association with better prognostic determinants while claudin-1 negative tumors may tend to be more often triple negative. Thus, IHC can be used in resource-constraint settings to substitute expensive molecular techniques.

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Publication Details

Journal
Iranian journal of pathology
Published
2024-10-01
DOI
https://doi.org/10.30699/ijp.2024.2028643.3299
Primary Topic
Epigenetics and DNA Methylation
Type
article
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article

Expression of Cyclin D1 and Claudin-1 in Invasive Breast Carcinoma and Their Correlation with Clinicopathological Parameters

Roopali Sehrawat, Vijay Shrawan Nijhawan, Vishesh Dhawan, Ayushi Kediya et al.
Iranian journal of pathology
Epigenetics and DNA Methylation
article

Expression of Cyclin D1 and Claudin-1 in Invasive Breast Carcinoma and Their Correlation with Clinicopathological Parameters

Roopali Sehrawat, Vijay Shrawan Nijhawan, Vishesh Dhawan, Ayushi Kediya, Maitrayee Roy
article en

Abstract

Our findings advocated the expression of IHC namely, cyclin D1 and claudin-1, in cases of breast cancer. Cyclin D1 positivity may show a significant association with better prognostic determinants while claudin-1 negative tumors may tend to be more often triple negative. Thus, IHC can be used in resource-constraint settings to substitute expensive molecular techniques.

Iranian journal of pathologyVol. 19(4)
Maharishi Markandeshwar University, Mullana (IN), Shree Guru Gobind Singh Tricentenary University (IN), Institute of Medical Sciences (IN)
Openalex Percentile: Top 78%
Epigenetics and DNA Methylation
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