The Immunostimulant Effect of Raspberry (Rubus idaeus) Fruit Ethanol Extract Through Carbon Clearance Index and Organ Index

Raspberry fruit ethanol extract is known to have strong antioxidant activity and which is related with immunostimulant activity. This study aims to determine the immunostimulant activity of ethanol extract of raspberry fruit.Raspberry fruit is macerated with 70% ethanol and concentrated using a rotary evaporator, then the phagocytosis index, spleen and liver index in mice are determined using the carbon clearence method.Based on the results obtained, it is known that all doses have immunostimulant activity because there are significant differences (p <0.05) between all doses against the negative control group with a dose of 400mg / kgBB having the highest value among the test groups and having moderate immunostimulant activity.