Effects of Low Intensity Focused Ultrasound Stimulation Combined With Functional Electrical Stimulation on Corticospinal Excitability and Upper Extremity Fine Motor Function
Real tbTUS+FES combined with voluntary movement results in immediate corticospinal inhibition with a return to BL at ∼20 min post-stimulation suggestive of homeostatic metaplasticity. These findings highlight the potential of tbTUS+FES as a neuromodulatory intervention, warranting further exploration in neurological conditions for therapeutic applications.
Authors
- Amitabh Bhattacharya (ORCID: https://orcid.org/0000-0002-0981-0494)
- Talyta Grippe (ORCID: https://orcid.org/0000-0003-3126-8002)
- Tarun Arora (ORCID: https://orcid.org/0000-0002-6484-4208)
- Naaz Kapadia (ORCID: https://orcid.org/0000-0001-7999-7488)
- Carolyn Gunraj
- Robert Chen (ORCID: https://orcid.org/0000-0002-8371-8629)
Institutions
- Oslo University Hospital (NO)
- University Health Network (CA)
- University of Toronto (CA)
- Toronto Western Hospital (CA)
- Ontario Brain Institute (CA)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/brb3.70318
- Citations
- 6
- Primary Topic
- Transcranial Magnetic Stimulation Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.05
Funders
- Canadian Institutes of Health Research
- Natural Sciences and Engineering Research Council of Canada