Discordance between endoscopic and histopathologic assessment in ileal Crohn’s disease
A striking discordance exists between endoscopic and histologic assessments for mucosal inflammation in patients with active ileal CD, even in biopsies targeted at an ulcer edge, while a higher concordance is seen in patients with no endoscopic disease activity. It remains unclear how to incorporate histologic disease activity into the treatment paradigm. Further research is needed to optimize biopsy protocols and histologic assessments for CD.
Authors
- Scott D Lee
- Kindra D Clark-Snustad
- Kendra Kamp (ORCID: https://orcid.org/0000-0002-7753-3564)
- Xianyong Gui (ORCID: https://orcid.org/0000-0001-8833-1098)
- Christian Avalos (ORCID: https://orcid.org/0000-0001-8852-9520)
- Brian Mau
Institutions
- Oregon Health & Science University (US)
- University of Washington (US)
- Neurobehavioral Systems (US)
- Wake Forest University (US)
Publication Details
- Journal
- World Journal of Gastrointestinal Endoscopy
- Published
- 2025-02-12
- DOI
- https://doi.org/10.4253/wjge.v17.i2.101284
- Citations
- 4
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 7.27