Axonal regeneration and innervation ratio following supercharged end-to-side nerve transfer
This novel SETS nerve transfer model enables isolated electrophysiological as well as histological evaluations of all nerve sections to determine the muscle innervation ratio exactly. Our findings indicate that substantial functional efferent muscle innervation by the donor nerve is exclusively observed in a regenerating environment.
Authors
- Oskar Christian Aszmann (ORCID: https://orcid.org/0000-0001-5530-726X)
- Leopold Harnoncourt (ORCID: https://orcid.org/0009-0001-8463-0397)
- Martin Schmoll (ORCID: https://orcid.org/0000-0001-6354-3879)
- Martin W. Breuss (ORCID: https://orcid.org/0000-0003-2200-8604)
- Christopher Festin (ORCID: https://orcid.org/0000-0003-4135-2590)
- Philipp Tratnig-Frankl (ORCID: https://orcid.org/0000-0002-9085-1604)
- Dominik C. Dotzauer (ORCID: https://orcid.org/0000-0003-2976-0559)
- Udo Maierhofer (ORCID: https://orcid.org/0000-0002-9122-1751)
- Johanna Klepetko (ORCID: https://orcid.org/0000-0003-4736-7558)
- Florian J. Jaklin (ORCID: https://orcid.org/0000-0001-5966-0781)
- Laurenz Pflaum
Institutions
- Medical University of Vienna (AT)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-02-12
- DOI
- https://doi.org/10.3389/fcell.2025.1513321
- Citations
- 2
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 1.82