Ultrasensitive interferons quantification reveals different cytokine profile secretion in inflammatory myopathies and can serve as biomarkers of activity in dermatomyositis
Serum IFN-α level measured by SIMOA is a reliable biomarker of DM activity. Myositis-specific antibodies appear to be associated with a different secretion profile. This data needs to be confirmed in order to select the good therapeutics strategies in DM.
Authors
- B. Hervier (ORCID: https://orcid.org/0000-0002-1388-1121)
- Damien Amelin
- Karim Dorgham (ORCID: https://orcid.org/0000-0001-9539-3203)
- Yves Allenbach (ORCID: https://orcid.org/0000-0002-3185-7993)
- L. Bolko (ORCID: https://orcid.org/0000-0002-0186-5570)
- Darragh Duffy (ORCID: https://orcid.org/0000-0002-8875-2308)
- K. Mariampillai (ORCID: https://orcid.org/0000-0002-0247-9276)
- Olivier Benvéniste (ORCID: https://orcid.org/0000-0002-1167-5797)
- Alba Llibre
- Mathieu Paul Rodero (ORCID: https://orcid.org/0000-0002-1300-0187)
- Vincent Bondet (ORCID: https://orcid.org/0000-0002-6534-0984)
- Solène Maillard
- Alexandrine Mahoudeau (ORCID: https://orcid.org/0000-0003-0027-5402)
- S. Toquet (ORCID: https://orcid.org/0000-0003-3800-1933)
- Océane Landon‐Cardinal
- C. Anquetil
- Guy Gorochov
- Samuel Malatre
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Institut Pasteur (FR)
- Université Paris Cité (FR)
- Sorbonne Université (FR)
- Sorbonne Paris Cité (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Centre Hospitalier Universitaire de Reims (FR)
- Institut de Myologie (FR)
- Pitié-Salpêtrière Hospital (FR)
- Centre d'Immunologie et des Maladies Infectieuses (FR)
- Centre Hospitalier de l’Université de Montréal (CA)
- Hôpital Maison Blanche (FR)
- Centre de Recherche en Myologie
- Université de Montréal (CA)
- Université de Reims Champagne-Ardenne (FR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-02-12
- DOI
- https://doi.org/10.3389/fimmu.2025.1529582
- Citations
- 5
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 6.77