CAV1 promotes epithelial-to-mesenchymal transition (EMT) and chronic renal allograft interstitial fibrosis by activating the ferroptosis pathway
CAV1 plays a critical role in the development of CAD by promoting EMT and chronic renal allograft interstitial fibrosis through the ferroptosis pathway. Adjusting ferroptosis by altering the expression abundance of CAV1 may become an important method for the prevention and treatment of CAD in the future.
Authors
- Jingwen Yuan (ORCID: https://orcid.org/0009-0008-5406-249X)
- Zijie Wang (ORCID: https://orcid.org/0000-0003-3831-3654)
- Ming Zheng (ORCID: https://orcid.org/0000-0003-2127-7589)
- Qianguang Han
- Bing Ni (ORCID: https://orcid.org/0000-0002-4297-5346)
- Zhijian Han
- Junqi Zhang (ORCID: https://orcid.org/0000-0002-0001-4555)
- Min Gu (ORCID: https://orcid.org/0000-0002-1000-5249)
- Xiaobing Ju
- Ruoyun Tan (ORCID: https://orcid.org/0009-0001-5052-5011)
- Jun Tao
- Wei Bao
- Jinxu Miu
Institutions
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Jiangsu Province Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-02-12
- DOI
- https://doi.org/10.3389/fimmu.2025.1523855
- Citations
- 2
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- National Natural Science Foundation of China