Aortic intimal sarcoma with abdominal metastasis: case report and management approach
Aortic intimal sarcoma is a rare neoplasm with limited treatment options. MDM2 overexpression is commonly observed, but similar histological features can appear in other conditions, making diagnosis challenging. Imaging modalities, including MRI and PET-CT, are crucial for diagnosis and monitoring. Current treatment strategies are non-standardized, but small-molecule inhibitors targeting MDM2 show promise. This case highlights the potential effectiveness of combined surgical and chemotherapeutic approaches for managing abdominal metastasis of aortic intimal sarcoma and provides a foundation for future clinical trials.
Authors
- Gehong Yao
- Jianwei Xu (ORCID: https://orcid.org/0000-0003-3945-5443)
Institutions
- Zhejiang Chinese Medical University (CN)
- Huzhou Normal University (CN)
- Huzhou Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-02-12
- DOI
- https://doi.org/10.3389/fonc.2025.1508691
- Primary Topic
- Cardiac tumors and thrombi
- Type
- article
- Field-Weighted Citation Impact
- 0.00