Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case report

The mortality of pulmonary embolism in children is high, and there is no standardized treatment protocol. We present a case of successful treatment of <i>Mycoplasma pneumoniae</i> (<i>M pneumoniae</i>) with pulmonary embolism in a child using rivaroxaban and doxycycline, thereby exploring a more appropriate treatment option. A 10-year-old male presented with fever, cough, and chest pain as the main symptoms. <i>M pneumoniae</i> polymerase chain reaction of bronchoalveolar lavage fluid was positive, and computed tomography angiography indicated pulmonary embolism. Azithromycin, doxycycline, and piperacillin-tazobactam were administered sequentially for infection control, while methylprednisolone was given to control inflammation and heparin and rivaroxaban for sequential treatment, resulting in a satisfactory recovery.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2025-02-12
DOI
https://doi.org/10.3389/fped.2025.1449493
Citations
3
Primary Topic
Pneumonia and Respiratory Infections
Type
article
Field-Weighted Citation Impact
4.06
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article

Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case report

LU He-min, Fang Xiaoqian
3 citations
Frontiers in Pediatrics
Pneumonia and Respiratory Infections
4.06
article

Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case report

LU He-min, Fang Xiaoqian
article en
3 citations

Abstract

The mortality of pulmonary embolism in children is high, and there is no standardized treatment protocol. We present a case of successful treatment of <i>Mycoplasma pneumoniae</i> (<i>M pneumoniae</i>) with pulmonary embolism in a child using rivaroxaban and doxycycline, thereby exploring a more appropriate treatment option. A 10-year-old male presented with fever, cough, and chest pain as the main symptoms. <i>M pneumoniae</i> polymerase chain reaction of bronchoalveolar lavage fluid was positive, and computed tomography angiography indicated pulmonary embolism. Azithromycin, doxycycline, and piperacillin-tazobactam were administered sequentially for infection control, while methylprednisolone was given to control inflammation and heparin and rivaroxaban for sequential treatment, resulting in a satisfactory recovery.

Frontiers in PediatricsVol. 13
Wenzhou Medical University (CN), Dongyang People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 7%
Pneumonia and Respiratory Infections
4.06
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