Case Report: Dangerous liaisons between splenectomy and eltrombopag-induced chronic thromboembolic pulmonary hypertension in patients with immune thrombocytopenia: report of two cases and review of the literature
In older patients, those with a history of thrombotic manifestations, or those with high-risk factors, clinicians should evaluate and monitor the risk of thrombotic events and chronic thromboembolic pulmonary hypertension when treating primary immune thrombocytopenia with splenectomy and Eltrombopag.
Authors
- Nicia I. Profili
- Giuseppe D. Sanna (ORCID: https://orcid.org/0000-0002-3357-0961)
- Pierluigi Merella (ORCID: https://orcid.org/0000-0001-6758-0343)
- Andrea Maria D’Armini (ORCID: https://orcid.org/0000-0002-7824-5249)
- Mattia Donadoni (ORCID: https://orcid.org/0000-0003-4952-0317)
- Roberto Manetti (ORCID: https://orcid.org/0000-0001-7376-2303)
- Salvatore Masala (ORCID: https://orcid.org/0000-0003-0032-7970)
- Enrico Atzori (ORCID: https://orcid.org/0000-0002-6836-8261)
- Roberto Castelli (ORCID: https://orcid.org/0000-0003-3976-7690)
- Enrico Ponti
- Alessandro Delitala (ORCID: https://orcid.org/0000-0003-1729-8969)
- Valentina Micheluzzi (ORCID: https://orcid.org/0000-0001-5780-6775)
- Gavino Casu (ORCID: https://orcid.org/0000-0001-9923-9473)
- Antonio Gidaro (ORCID: https://orcid.org/0000-0002-5379-1091)
- Dante Daniel Castro
Institutions
- University of Sassari (IT)
- University of Milan (IT)
- University of Pavia (IT)
- Luigi Sacco Hospital (IT)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-02-12
- DOI
- https://doi.org/10.3389/fcvm.2025.1508574
- Citations
- 1
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.77