High-throughput in vitro drug screening and in vivo studies identify fenretinide as a brain-penetrant DMG therapeutic

This comprehensive study has identified new DMG therapeutic vulnerabilities and highlights fenretinide as a brain-penetrant, anti-DMG agent.

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Institutions

Publication Details

Journal
Neuro-Oncology
Published
2025-02-12
DOI
https://doi.org/10.1093/neuonc/noaf035
Citations
1
Primary Topic
Retinoids in leukemia and cellular processes
Type
article
Field-Weighted Citation Impact
0.81
Controls
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article

High-throughput in vitro drug screening and in vivo studies identify fenretinide as a brain-penetrant DMG therapeutic

Maria Tsoli, Han Shen, Aaminah Khan, Nicole Yeung et al.
1 citations
Neuro-Oncology
Retinoids in leukemia and cellular processes
0.81
article

High-throughput in vitro drug screening and in vivo studies identify fenretinide as a brain-penetrant DMG therapeutic

Maria Tsoli, Han Shen, Aaminah Khan, Nicole Yeung, Dannielle Upton, David S. Ziegler, Santosh Valvi, Chelsea Mayoh, Giovanna Farruggia, C. Patrick Reynolds, Benjamin S. Rayner, Anjana Gopalakrishnan, Isabella Orienti, Pooja Venkat, Anahid Ehteda, Caitlin Ung, Laura Franshaw, Holly Holliday, Jie Liu, Sandra George, Hieu Trung Nguyen, Ruby Pandher
article en
1 citations

Abstract

This comprehensive study has identified new DMG therapeutic vulnerabilities and highlights fenretinide as a brain-penetrant, anti-DMG agent.

Neuro-OncologyVol. 27(7)
Texas Tech University (US), Cancer Institute of New South Wales (AU), UNSW Sydney (AU), Sydney Children's Hospital (AU), Texas Tech University Health Sciences Center (US), University of Bologna (IT)
Good health and well-being
Openalex Percentile: Top 31%
Retinoids in leukemia and cellular processes
0.81
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High-throughput in vitro drug screening and in vivo studies identify fenretinide as a brain-penetrant DMG therapeutic — Maria Tsoli, Han Shen, et al. · Neuro-Oncology (2025) | TGRS Research Map | TGRS