Parallelization of a Method to Infer Genetic Networks in Multi-CPU Systems

Genetic regulatory networks represent the interactions present between genes and are a crucial step in understanding cellular physiology and complex pathological phenotypes. There are various methods to infer these networks from a set of genetic data. Among them, the MRNET method stands out, which is based on the mRMR feature selection algorithm. However, constructing genetic regulatory networks with MRNET is a computationally expensive process for large-scale datasets due to its cubic complexity concerning the number of genes. The objective of this work is to develop parallel versions of MRNET that can be executed on shared-memory parallel systems to accelerate its execution.

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Publication Details

Published
2024-11-01
DOI
https://doi.org/10.17979/spudc.9788497498913.5
Primary Topic
Evolutionary Algorithms and Applications
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article
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article

Parallelization of a Method to Infer Genetic Networks in Multi-CPU Systems

Javier Gómez Darriba, Jorge Méndez González
Evolutionary Algorithms and Applications
article

Parallelization of a Method to Infer Genetic Networks in Multi-CPU Systems

Javier Gómez Darriba, Jorge Méndez González
article en

Abstract

Genetic regulatory networks represent the interactions present between genes and are a crucial step in understanding cellular physiology and complex pathological phenotypes. There are various methods to infer these networks from a set of genetic data. Among them, the MRNET method stands out, which is based on the mRMR feature selection algorithm. However, constructing genetic regulatory networks with MRNET is a computationally expensive process for large-scale datasets due to its cubic complexity concerning the number of genes. The objective of this work is to develop parallel versions of MRNET that can be executed on shared-memory parallel systems to accelerate its execution.

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Evolutionary Algorithms and Applications
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