Global, regional and national trends in incidence and mortality of pertussis from 1990 to 2021 and the comparison before and during COVID-19: A modelling analysis

From 1990-2021, global burden of pertussis showed a downward trend, with significant drops during the COVID-19 pandemic. However, before the COVID-19, Southern Sub-Saharan Africa saw rising ASIR and ASDR, contrary to the majority. Besides, SDI was proved negatively correlated with ASR, indicating that low-SDI countries, especially in Sub-Saharan Africa, faced high disease burden, which highlighted the need for improving immunization, surveillance, and healthcare resource allocation to control pertussis effectively.