Anti-Cancer Bioactive Peptide Induces Apoptosis in Gastric Cancer Cells through TP53 Signaling Cascade

Notably, after ACBP treatment, Mcl-1 expression was significantly reduced in the tumor tissue of the xenograft model, indicating that ACBP induced apoptosis through the TP53 signaling cascade. This project provides a scientific basis for exploring the antitumor mechanism of ACBP in gastric cancer therapy.

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Publication Details

Journal
Protein and Peptide Letters
Published
2025-02-12
DOI
https://doi.org/10.2174/0109298665350654250111144722
Citations
8
Primary Topic
Cancer, Lipids, and Metabolism
Type
article
Field-Weighted Citation Impact
7.49
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article

Anti-Cancer Bioactive Peptide Induces Apoptosis in Gastric Cancer Cells through TP53 Signaling Cascade

Xiulan Su, Qimuge Suyila, Xian Li
8 citations
Protein and Peptide Letters
Cancer, Lipids, and Metabolism
7.49
article

Anti-Cancer Bioactive Peptide Induces Apoptosis in Gastric Cancer Cells through TP53 Signaling Cascade

Xiulan Su, Qimuge Suyila, Xian Li
article en
8 citations

Abstract

Notably, after ACBP treatment, Mcl-1 expression was significantly reduced in the tumor tissue of the xenograft model, indicating that ACBP induced apoptosis through the TP53 signaling cascade. This project provides a scientific basis for exploring the antitumor mechanism of ACBP in gastric cancer therapy.

Protein and Peptide LettersVol. 32(3)
Inner Mongolia Medical University (CN)
Good health and well-being
Openalex Percentile: Top 3%
Cancer, Lipids, and Metabolism
7.49
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