Application of Probiotics and Postbiotics in Neurological Disorders

Neurological illnesses encompass a broad spectrum of conditions that affect the brain, spine, and nerves, often impairing daily functioning. The global prevalence of these illnesses is rising, posing significant health challenges. This study investigates the beneficial effects of probiotics and postbiotics in managing various neurological disorders, providing a comprehensive analysis of their use in treating these conditions. The article explores innovative, holistic approaches to neurological care, emphasizing patient-centered therapeutic interventions. Compelling evidence suggests that probiotics and postbiotics positively impact several neurological diseases. Specifically, the findings indicate that these treatments can modulate the gut-brain axis, reduce neuroinflammation, and enhance neuronal protection. The study highlights the potential of specific bacteria and their byproducts to ameliorate neurological disorders. Despite promising results, the current data underscore the challenges in future research on the therapeutic benefits of probiotics and postbiotics for neurological illnesses and underscores the critical role of the gut-brain connection and the microbiome in maintaining neurological health. It also examines the safety and feasibility of using probiotics and postbiotics as adjunct therapies, delving into the mechanisms underlying their beneficial effects. Probiotics and postbiotics demonstrate a capacity to enhance the regenerative potential of the human brain, and recent evaluations provide additional evidence supporting their efficacy and safety. However, further rigorous clinical trials are necessary to validate these findings and establish the most effective therapeutic strategies for treating neurological disorders.

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Publication Details

Journal
Current Pharmaceutical Biotechnology
Published
2025-02-12
DOI
https://doi.org/10.2174/0113892010336767250128072101
Citations
1
Primary Topic
Medicinal Plants and Bioactive Compounds
Type
article
Field-Weighted Citation Impact
0.81
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article

Application of Probiotics and Postbiotics in Neurological Disorders

Mahdi Asghari Ozma, Bahareh Mehramuz, Hossein Samadi Kafil, Khudaverdi Ganbarov et al.
1 citations
Current Pharmaceutical Biotechnology
Medicinal Plants and Bioactive Compounds
0.81
article

Application of Probiotics and Postbiotics in Neurological Disorders

Mahdi Asghari Ozma, Bahareh Mehramuz, Hossein Samadi Kafil, Khudaverdi Ganbarov, Afsoon Asadollahi, Darya Mohammadpour
article en
1 citations

Abstract

Neurological illnesses encompass a broad spectrum of conditions that affect the brain, spine, and nerves, often impairing daily functioning. The global prevalence of these illnesses is rising, posing significant health challenges. This study investigates the beneficial effects of probiotics and postbiotics in managing various neurological disorders, providing a comprehensive analysis of their use in treating these conditions. The article explores innovative, holistic approaches to neurological care, emphasizing patient-centered therapeutic interventions. Compelling evidence suggests that probiotics and postbiotics positively impact several neurological diseases. Specifically, the findings indicate that these treatments can modulate the gut-brain axis, reduce neuroinflammation, and enhance neuronal protection. The study highlights the potential of specific bacteria and their byproducts to ameliorate neurological disorders. Despite promising results, the current data underscore the challenges in future research on the therapeutic benefits of probiotics and postbiotics for neurological illnesses and underscores the critical role of the gut-brain connection and the microbiome in maintaining neurological health. It also examines the safety and feasibility of using probiotics and postbiotics as adjunct therapies, delving into the mechanisms underlying their beneficial effects. Probiotics and postbiotics demonstrate a capacity to enhance the regenerative potential of the human brain, and recent evaluations provide additional evidence supporting their efficacy and safety. However, further rigorous clinical trials are necessary to validate these findings and establish the most effective therapeutic strategies for treating neurological disorders.

Current Pharmaceutical BiotechnologyVol. 27(2)
Tabriz University of Medical Sciences (IR), Baku State University (AZ), Urmia University (IR), Urmia University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 31%
Medicinal Plants and Bioactive Compounds
0.81
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