The Suicide Gene System Cytosine Deaminase::Uracylphosphoribosyltransferase/5-fluorocytosine Displays a Strong Cytotoxic Effect on Human Melanoma Cells
This suicide gene therapy approach, amplified by the release of free 5-fluorouracil and soluble and particulate factors containing CD::UPRT genetic information and/or enzyme, could have a great clinical potential for malignant melanoma.
Authors
- Gerardo C. Glikin (ORCID: https://orcid.org/0000-0002-7162-5409)
- Liliana María Elena Finocchiaro
- Sofía Gala Bernabei-Cornejo
Institutions
- Universidad de Buenos Aires (AR)
- Instituto de Oncología de Rosario (AR)
Publication Details
- Journal
- Current Pharmaceutical Biotechnology
- Published
- 2025-02-12
- DOI
- https://doi.org/10.2174/0113892010319891241121115002
- Primary Topic
- Biochemical and Molecular Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00