Use of Advanced Echocardiographic Modalities to Discriminate Preclinical Hypertrophic Cardiomyopathy Mutation Carriers From Non-Carriers
In HCM family members, color M-mode velocity propagation and apical rotation provide good sensitivity and specificity for identifying mutation carriers and may represent early disease markers before the onset of hypertrophy. Longitudinal studies involving larger cohorts are required to validate these findings.
Authors
- Arnold C.T. Ng (ORCID: https://orcid.org/0000-0002-1925-9958)
- T. Mew (ORCID: https://orcid.org/0000-0002-4447-297X)
- Julie McGaughran (ORCID: https://orcid.org/0000-0002-0926-7858)
- John James Atherton (ORCID: https://orcid.org/0000-0003-2271-578X)
- K. Guppy-Coles (ORCID: https://orcid.org/0000-0002-2928-2983)
- S. Prasad (ORCID: https://orcid.org/0000-0002-8681-9425)
- Louise McCormack
- Christina Mew (ORCID: https://orcid.org/0000-0003-2786-301X)
- Arun Dahiya (ORCID: https://orcid.org/0000-0002-3433-3255)
- Adrian Lo (ORCID: https://orcid.org/0000-0002-4397-7618)
Institutions
- Griffith University (AU)
- Queensland University of Technology (AU)
- The University of Queensland (AU)
- Royal Brisbane and Women's Hospital (AU)
- Princess Alexandra Hospital (AU)
- Anna Needs Neuroblastoma Answers (US)
- Princess Alexandra Hospital (GB)
Publication Details
- Journal
- Circulation Genomic and Precision Medicine
- Published
- 2025-02-12
- DOI
- https://doi.org/10.1161/circgen.124.004806
- Citations
- 1
- Primary Topic
- Cardiomyopathy and Myosin Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.39