Advancing neuroprotection and atherosclerosis prevention through familial hypercholesterolemia management: Analyzing comorbidity burden with stroke, coronary heart disease, hypertension, and diabetes
With a large number of patients with dyslipidemia, the type and number of comorbidities significantly impact the healthcare burden. FH presents with earlier onset, more comorbidities, and heavier cardiovascular-related medical burdens than HC. Early identification, intervention, and comprehensive management of comorbidities in the FH population are crucial for neuroprotection and prevention of atherosclerotic cardiovascular disease.
Authors
- Jingjia Wang (ORCID: https://orcid.org/0000-0003-1556-9315)
- Xuliang Wang (ORCID: https://orcid.org/0000-0001-6520-6948)
- Jun Gao (ORCID: https://orcid.org/0000-0003-4637-1918)
- Zhiyun Yang (ORCID: https://orcid.org/0000-0002-6139-9049)
- Pei Gao (ORCID: https://orcid.org/0000-0001-8649-1290)
- Siyan Zhan (ORCID: https://orcid.org/0000-0001-7252-5349)
- Jilin Zheng (ORCID: https://orcid.org/0009-0009-8611-6402)
- Wei Chen (ORCID: https://orcid.org/0000-0003-1466-824X)
- Da Liu (ORCID: https://orcid.org/0000-0003-3994-2786)
- Jun Wen (ORCID: https://orcid.org/0000-0003-0861-5803)
- Sicong Liu (ORCID: https://orcid.org/0000-0003-1612-4844)
- Ming Zhang (ORCID: https://orcid.org/0000-0003-4116-8144)
- Lin Yang (ORCID: https://orcid.org/0000-0002-1826-6064)
- Xiangbin Meng (ORCID: https://orcid.org/0000-0002-4252-7869)
- Chunli Shao (ORCID: https://orcid.org/0000-0001-6366-1285)
- Wenyao Wang (ORCID: https://orcid.org/0000-0001-9897-2761)
Institutions
- Hebei Medical University (CN)
- Chinese Academy of Sciences (CN)
- Peking University (CN)
- SGIDI Engineering Consulting (China) (CN)
- Academy of Mathematics and Systems Science (CN)
- Peng Cheng Laboratory (CN)
- Peking University Third Hospital (CN)
- Beijing Chuiyangliu Hospital (CN)
- First Affiliated Hospital of Hebei Medical University (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Neuroprotection/Neuroprotection (Chichester, England. Print)
- Published
- 2025-02-12
- DOI
- https://doi.org/10.1002/nep3.72
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Peking University