Innovative Therapies: A Major Breakthrough in Combating Multi-Drugresistant Bacterial Infections Using Mixture Design and Multi-Objective Optimization with NSGA-II Algorithm
The consistent and reliable predictions for bacterial strains affirmed the robustness of the applied methodology. These results not only pave the way for further exploration but also offer valuable insights for optimizing pharmaceutical and medical interventions, presenting innovative avenues for combating antibiotic-resistant bacterial infections.
Authors
- Hichem Tahraoui (ORCID: https://orcid.org/0000-0003-2209-6405)
- Khodir Madani (ORCID: https://orcid.org/0000-0001-5356-6890)
- Farid Dahmoune (ORCID: https://orcid.org/0000-0001-6072-0411)
- Abdeltif Amrane (ORCID: https://orcid.org/0000-0003-2622-2384)
- Hocine Remini (ORCID: https://orcid.org/0000-0001-7006-9618)
- Nabil Kadri (ORCID: https://orcid.org/0000-0003-1158-696X)
- Meriem Adouane (ORCID: https://orcid.org/0000-0002-0112-9776)
- Nourelimane Benzitoune
- Samia Djellal
- Chafika Lakhdari
- Lilla Ousmer
Institutions
- Centre National de la Recherche Scientifique (FR)
- University of Béjaïa (DZ)
- University of Bouira (DZ)
- University Ferhat Abbas of Setif (DZ)
- Institut des Sciences Chimiques de Rennes (FR)
- École Nationale Supérieure de Chimie de Rennes (FR)
- Centre de Recherche en Technologies Agro-Alimentaires
- Université de Rennes (FR)
Publication Details
- Journal
- Current Topics in Medicinal Chemistry
- Published
- 2025-02-12
- DOI
- https://doi.org/10.2174/0115680266333406250126033304
- Citations
- 1
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.59