Exploring the Impact of Curcumin and Carbon Nanotubes on BetaAmyloid Peptide Dimer: Insights from Molecular Dynamics Simulationand Density Functional Theory Methods

Curcumin plays a significant role in destabilizing beta-amyloid dimers and reducing their toxicity, with its effect being modulated by the presence of carbon nanotubes. This dual influence highlights the potential of using curcumin, alongside nanomaterials, in therapeutic strategies for neurodegenerative diseases. This study provided valuable insights into the molecular interactions among curcumin, beta-amyloid peptides, and carbon nanotubes. These findings can contribute to the development of more effective treatments targeting amyloid-related toxicity in neurodegenerative conditions.