Effects of Spirulina Supplementation on Blood Biochemical Parameters during a Malnutrition and Refeeding Trial in Wistar Rats

This study aims to evaluate the effects of Spirulina (Spirulina platensis) supplementation on blood biochemical parameters during malnutrition and refeeding trials in Wistar rats (Rattus norvegicus). Thirty rats were divided into five groups, three of which received varying doses of Spirulina (10, 50, and 100 mg/kg) in addition to standard FACI® pellets. The experiment lasted 15 days, including a malnutrition phase followed by a refeeding phase. The results indicated significant recovery in body weight and blood biochemical parameters. The best outcomes were observed in rats that received 100 mg/kg of Spirulina. These findings suggest that Spirulina is a promising nutritional supplement for restoring malnutrition-induced abnormalities.