Faricimab efficacy in a poorly responsive case of Polypoidal Choroidal Vasculopathy (PCV): A case report

PurposeTo evaluate anatomical and functional outcomes of Faricimab therapy on a case of polypoidal choroidal vasculopathy (PCV) refractory to previous treatments.Major findingsA 56-year-old patient with PCV presenting with a large pigment epithelial detachment (PED) showed best-corrected visual acuity (BCVA) improvement, subretinal fluid (SRF) reduction and PED height reduction at 2 months follow up after a loading phase of 4 monthly Faricimab injections. The patient had previously undergone Aflibercept, Brolucizumab and photodynamic therapy (PDT) treatments with a suboptimal response.ConclusionDespite Faricimab proving itself as an efficient alternative in a case of PCV poorly responsive to previous treatments, definite evidence still needs to be confirmed in larger studies.

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Publication Details

Journal
European Journal of Ophthalmology
Published
2025-02-12
DOI
https://doi.org/10.1177/11206721241310629
Citations
1
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
1.71
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article

Faricimab efficacy in a poorly responsive case of Polypoidal Choroidal Vasculopathy (PCV): A case report

Clara Rizzo, Raphael Kilian, Maria Cristina Savastano, Stanislao Rizzo
1 citations
European Journal of Ophthalmology
Retinal Diseases and Treatments
1.71
article

Faricimab efficacy in a poorly responsive case of Polypoidal Choroidal Vasculopathy (PCV): A case report

Clara Rizzo, Raphael Kilian, Maria Cristina Savastano, Stanislao Rizzo
article en
1 citations

Abstract

PurposeTo evaluate anatomical and functional outcomes of Faricimab therapy on a case of polypoidal choroidal vasculopathy (PCV) refractory to previous treatments.Major findingsA 56-year-old patient with PCV presenting with a large pigment epithelial detachment (PED) showed best-corrected visual acuity (BCVA) improvement, subretinal fluid (SRF) reduction and PED height reduction at 2 months follow up after a loading phase of 4 monthly Faricimab injections. The patient had previously undergone Aflibercept, Brolucizumab and photodynamic therapy (PDT) treatments with a suboptimal response.ConclusionDespite Faricimab proving itself as an efficient alternative in a case of PCV poorly responsive to previous treatments, definite evidence still needs to be confirmed in larger studies.

European Journal of OphthalmologyVol. 35(3)
Università Cattolica del Sacro Cuore (IT), University of Verona (IT), University of Ferrara (IT), Agostino Gemelli University Polyclinic (IT), Neuroscience Institute (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Good health and well-being
Openalex Percentile: Top 22%
Retinal Diseases and Treatments
1.71
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