Effect of Croton bonplandianum & Acalypha indica Plant Extracts on Septic Arthritis Causing Microbes

Septic arthritis is an acute inflammatory disorder caused by microbial infection, affecting the joint fluid and joint tissues. Today, treatment for infections caused by microorganisms is a major problem with growing antibiotic resistance and slow pace in the discovery of new antibiotics. Perhaps, plant extracts with antimicrobial components are the promising drugs for the future which help in overcoming the crisis aroused due to antibiotic resistance. In the current study, ethyl acetate, chloroform and methanol extracts of two weeds namely Croton bonplandianum (aerial parts and roots) and Acalypha indica (aerial parts) were studied for their in-vitro anti-arthritic activity against septic arthritis causing microorganisms. The ethyl acetate, chloroform and methanol extracts of Croton bonplandianum was found to be effective against all the test organisms including multidrug resistant Pseudomonas aerogenosa. Therefore, it is been identified as the promising source of potent bioactive compounds with anti-arthritic activity.