Psychological Distress and Quality of Life in Families With a Germline <i>CDKN2A</i> Pathogenic Variant
In conclusion, confirmed and at-risk carriers of the CDKN2A PV under cancer surveillance experienced similar levels of QoL and general distress compared to the general population. However, cancer-related worry was substantial in this population. These findings can help identify individuals who may benefit from psychological support.
Authors
- Derk C.F. Klatte (ORCID: https://orcid.org/0000-0003-2531-6725)
- Chris Hinnen (ORCID: https://orcid.org/0000-0001-6085-4065)
- Thomas P. Potjer (ORCID: https://orcid.org/0000-0002-3831-6022)
- Remco van Doorn (ORCID: https://orcid.org/0000-0002-7019-6673)
- Anke Onnekink (ORCID: https://orcid.org/0000-0002-1241-1523)
- Monique Esther van Leerdam (ORCID: https://orcid.org/0000-0002-5719-3208)
- Jeanin E. van Hooft (ORCID: https://orcid.org/0000-0002-4424-0079)
- Eveline M. A. Bleiker (ORCID: https://orcid.org/0000-0003-4357-949X)
- S. M. S. van der Zwaan
- S. H. van den Berg
Institutions
- Leiden University Medical Center (NL)
- Jacksonville College (US)
- The Netherlands Cancer Institute (NL)
- Mayo Clinic in Florida (US)
- Spaarne Gasthuis (NL)
Publication Details
- Journal
- Molecular Genetics & Genomic Medicine
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/mgg3.70045
- Citations
- 1
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.82