Dynamic changes in peripheral blood immunophenotyping and its prognostic value in cervical cancer patients undergoing immune checkpoint blockade therapy
Our study demonstrated the potential proliferation of peripheral blood anti-tumor T cells in some CC patients undergoing ICB therapy. The observed associations between peripheral blood immunophenotyping and OS suggest that these biomarkers might have potential as prognostic tools.
Authors
- Nengxian Wu
- Xiaoying Xu (ORCID: https://orcid.org/0000-0001-5149-9487)
- Lu Zhou
- Hongyu Yao (ORCID: https://orcid.org/0000-0002-6626-2682)
- Maomao Wang (ORCID: https://orcid.org/0000-0003-0305-1834)
- Zhijiong Huang (ORCID: https://orcid.org/0000-0001-5868-2137)
- Wenjian Gong (ORCID: https://orcid.org/0009-0001-3247-1224)
- Lu Huang (ORCID: https://orcid.org/0000-0002-7820-2177)
- Qi Gan (ORCID: https://orcid.org/0000-0001-7963-0459)
- Kuina Li
- Bingbing Yan
- Zhijun Yang (ORCID: https://orcid.org/0000-0002-2255-4034)
- Zhi Wang (ORCID: https://orcid.org/0000-0002-5276-1413)
- Xiaoqi Chen (ORCID: https://orcid.org/0000-0003-2920-9951)
- Bing Zhao (ORCID: https://orcid.org/0000-0001-5999-9240)
- Xiaoling Huang (ORCID: https://orcid.org/0000-0002-1500-6822)
- Yongqiang Wei (ORCID: https://orcid.org/0000-0002-4054-1923)
Institutions
- Guangxi University (CN)
- Guangxi Medical University (CN)
- Guangxi Center for Disease Prevention and Control (CN)
- Tumor Hospital of Guangxi Medical University (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-02-12
- DOI
- https://doi.org/10.1007/s12672-025-01943-3
- Citations
- 2
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Natural Science Foundation of Guangxi Zhuang Autonomous Region
- Natural Science Foundation of Guangxi Province