Comparative efficacy of biologics and small molecule drugs in treating pediatric atopic dermatitis in patients aged 2–18 years: A 12–16 week network meta‐analysis of randomized controlled trials

This analysis establishes a hierarchy of effectiveness among systemic therapies for pediatric AD, with upadacitinib showing highest efficacy. However, the predominance of adolescent data emphasizes the need for age-stratified studies in younger children and long-term safety assessments.

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Publication Details

Journal
Pediatric Allergy and Immunology
Published
2025-02-01
DOI
https://doi.org/10.1111/pai.70045
Citations
5
Primary Topic
Dermatology and Skin Diseases
Type
article
Field-Weighted Citation Impact
10.02
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article

Comparative efficacy of biologics and small molecule drugs in treating pediatric atopic dermatitis in patients aged 2–18 years: A 12–16 week network meta‐analysis of randomized controlled trials

Chang‐Ching Wei, Xuan‐Yi Huang, Berne Ting, Li Jingling et al.
5 citations
Pediatric Allergy and Immunology
Dermatology and Skin Diseases
10.02
article

Comparative efficacy of biologics and small molecule drugs in treating pediatric atopic dermatitis in patients aged 2–18 years: A 12–16 week network meta‐analysis of randomized controlled trials

Chang‐Ching Wei, Xuan‐Yi Huang, Berne Ting, Li Jingling, Jiu‐Yao Wang, Su‐Boon Yong, Ikbal Andrian Malau, Suet‐Kei Wu
article en
5 citations

Abstract

This analysis establishes a hierarchy of effectiveness among systemic therapies for pediatric AD, with upadacitinib showing highest efficacy. However, the predominance of adolescent data emphasizes the need for age-stratified studies in younger children and long-term safety assessments.

Pediatric Allergy and ImmunologyVol. 36(2)
China Medical University (TW), China Medical University Hospital (TW), National Yang Ming Chiao Tung University (TW)
Good health and well-being
Openalex Percentile: Top 2%
Dermatology and Skin Diseases
10.02
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